Highlights
- •RNA-targeting Cas9 (RCas9) enabled recognition of endogenous, unmodified mRNAs
- •RCas9 did not influence mRNA abundance or amount of translated protein
- •Subcellular distribution of RCas9 was highly correlated with RNA-FISH
- •RCas9 revealed trafficking of mRNAs to stress granules in live cells
- •RNA-targeting Cas9 (RCas9) enabled recognition of endogenous, unmodified mRNAs
- •RCas9 did not influence mRNA abundance or amount of translated protein
- •Subcellular distribution of RCas9 was highly correlated with RNA-FISH
- •RCas9 revealed trafficking of mRNAs to stress granules in live cells
No comments:
Post a Comment